Description
ACTOVEGIN tablets, 200 mg, #50
Composition
Each ACTOVEGIN tablet contains 200 mg of deproteinized hemoderivative from calf blood (dry matter). Excipients: magnesium stearate, cellulose, colloidal silicon dioxide, povidone. Coating ingredients: talc, titanium dioxide, macrogol 6000, hypromellose, red and yellow iron oxides.
Description
ACTOVEGIN is a metabolic agent that enhances cellular energy utilization. It is used to improve oxygen and glucose uptake by tissues under conditions of impaired circulation. Available in tablet form, each pack includes 50 coated tablets for oral administration.
Pharmacological Action
ACTOVEGIN stimulates cellular metabolism by increasing glucose and oxygen uptake. This leads to improved ATP synthesis and enhances energy-dependent processes in cells. It supports tissue regeneration and repair, particularly under ischemic or hypoxic conditions.
Indications
- Peripheral circulatory disorders (arterial/venous) and complications such as diabetic polyneuropathy
- Ischemic stroke and post-stroke recovery
- Cognitive disorders due to chronic cerebrovascular insufficiency
- Delayed wound healing and tissue repair
Dosage and Administration
Standard oral dose: 1–2 tablets, three times per day, before meals. Swallow tablets whole with water. Dosage and treatment duration should be individualized by a physician depending on the clinical condition.
Contraindications
- Hypersensitivity to ACTOVEGIN or its components
- Severe heart failure, pulmonary edema, or fluid retention (oliguria/anuria)
Side Effects
- Allergic reactions (rash, itching, urticaria)
- Hot flushes and skin redness
- Increased heart rate (tachycardia)
- Fever, chills (in rare cases)
Overdose
No specific overdose symptoms reported. If overdose is suspected, seek immediate medical attention. Symptomatic treatment should be provided.
Drug Interactions
No documented interactions with other medications. However, as with any drug, patients should inform their doctor of all concurrent medications, including over-the-counter and herbal products.
Precautions
- Use with caution in patients with cardiovascular or renal impairment
- Monitor for allergic responses, especially after initial dosing
- Patients with diabetes should monitor blood glucose levels during treatment
Use During Pregnancy and Lactation
ACTOVEGIN can be used during pregnancy and breastfeeding only under medical supervision when the expected benefits outweigh potential risks.
Storage
Store in a dry, light-protected place at temperatures not exceeding 25°C. Keep out of reach of children.
Packaging
Each package contains 50 coated tablets, 200 mg each. Tablets are greenish-yellow, round, biconvex, with a glossy finish.
Manufacturer
Takeda Pharmaceuticals
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