Main active ingredient: epinephrine.

Inactive ingredients: sodium metabisulfite, sodium chloride, water for injection.

The medication is produced in the form of injection solution packed in 1 ml ampoules. Each 1 ml of medication contains 1.8 mg of epinephrine.

Description

Adrenaline is a sympathomimetic stimulant similar in structure to amphetamine and methamphetamine. Epinephrine provides the same effect as the adrenergic hormone in our body – adrenaline. Individuals taking epinephrine experience a strong increase in the intensity of the central nervous system, and it stimulates other body systems. Athletes also use adrenaline.

Pharmacologic Effect

Adrenaline inhibits mucus secretion from the blood vessels of tissues, improves airway patency, and enhances mental activity. It improves blood pressure, increases the minute volume of blood circulation, heart contraction frequency and strength, atrioventricular conduction, muscle tone, pupil dilation, and central nervous system stimulation. It also reduces edema in urticaria.

Properties

Some athletes take epinephrine about an hour before training and during competitions for stimulation. Slight improvements in power and energy can enhance anaerobic capacity and the performance of basic lifts. To achieve these effects, use a dosage of 25-50 mg. Adrenaline should not be used regularly due to its addictive nature. Usually, epinephrine is taken 2-3 times per week.

Use of Medication

Contraindications

• The medication is contraindicated for use if the patient has severe hypersensitivity (allergy) to the main or any of the inactive ingredients.
• Hypertrophic obstructive cardiomyopathy
• Severe aortic stenosis
• Tachyarrhythmias, ventricular fibrillation
• Pheochromocytoma, angle-closure glaucoma
• Shock (except for anaphylactic shock)
• General anesthesia with inhalation elements: fluorothane, cyclopropane, chloroform

Do not apply on fingers, nose, genitals.

• Increased blood pressure, tachyarrhythmia, bradycardia, other heart rhythm disturbances
• Pallor of skin, vomiting, fear, anxiety, tremors, headache
• Metabolic acidosis, myocardial infarction, cranial hemorrhage (especially in elderly patients)
• Pulmonary edema, renal failure, death (minimum lethal dose for subcutaneous use is 10 ml)

In case of overdosage, discontinue medication use, take alpha and beta-blockers, and fast-acting nitrates.

Side Effects

• Angina pectoris, bradycardia, tachycardia, shortness of breath, arrhythmia
• Decrease or increase in blood pressure
• Headache, tremors, dizziness, nervousness
• Anxiety, psychoneurotic disorders, paranoia, sleep disturbance
• Nausea, vomiting, anorexia
• Difficult and painful urination (with prostatic hyperplasia)
• Rash, erythema multiforme
• Hypokalemia, hyperglycemia
• Angioedema, bronchospasm
• Pain or burning at the site of intramuscular injection
• Increased sweating, impairment, necrosis due to the vasoconstrictor action of adrenaline (including necrosis of the liver or kidneys)

Storage Terms and Conditions

Shelf life is 2 years.

Storage temperature should not exceed 15°C. Do not freeze!