Description

NeoTad (Glutathione with Vitamin C, powder, 20 sachets of 2g) Solution

Composition

Each 2g sachet of NeoTad contains:

• Glutathione: A tripeptide composed of glutamine, cysteine, and glycine. It functions as a major intracellular antioxidant.
• Vitamin C (Ascorbic Acid): A water-soluble vitamin and antioxidant crucial for immune function and tissue repair.
• Other excipients: Natural flavorings, stabilizers, and binding agents (may vary depending on manufacturer).

Description

NeoTad is an oral dietary supplement presented as a white-to-off-white powder in individual 2g sachets. It is intended to be dissolved in water or juice prior to ingestion. The formulation combines glutathione with vitamin C to synergistically support cellular defense, skin health, detoxification, and immunity.

Pharmacological Properties

• Glutathione is the body’s primary endogenous antioxidant. It protects cellular components from oxidative damage, detoxifies xenobiotics through conjugation, supports immune response, and regenerates other antioxidants such as vitamins C and E. It also influences melanogenesis, making it popular in dermatology for skin tone balance.
• Vitamin C acts as an electron donor for various enzymatic reactions, supports collagen synthesis, enhances iron absorption, and regenerates glutathione in oxidized form. It is a co-factor in carnitine synthesis and neuropeptide metabolism.

Co-administration of glutathione and vitamin C improves the pharmacokinetic profile and intracellular retention of glutathione, as vitamin C stabilizes its reduced form and inhibits oxidative degradation.

Indications

NeoTad is recommended as a supportive therapy in the following cases:

• General antioxidant support and immune enhancement
• Skin rejuvenation, pigmentation modulation, and dermatological health
• Support during detoxification protocols
• Oxidative stress-related conditions (e.g., chronic inflammation, pollution exposure)
• Supportive therapy during chemotherapy, liver disease, or HIV treatment (under medical supervision)

Contraindications

• Known hypersensitivity to glutathione, vitamin C, or formulation excipients
• Patients with oxalate kidney stones or renal impairment (due to high-dose vitamin C)
• Pregnant or breastfeeding women without physician recommendation

Dosage and Administration

• Standard dose: One sachet (2g) once daily
• Administration: Dissolve in 150–200 ml of water or juice; consume immediately after preparation
• May be taken with or without food
• Dosage may be increased to twice daily under medical supervision for intensive therapy

Overdose and Management

Overdose is uncommon but may result in symptoms such as:

• Nausea
• Abdominal cramps
• Diarrhea
• Oxaluria (from excessive vitamin C intake)

Supportive and symptomatic care is advised in overdose cases. Maintain hydration and monitor renal function if necessary.

Side Effects

• Occasional gastrointestinal discomfort (nausea, bloating, or diarrhea)
• Rare allergic reactions: rash, pruritus, or swelling
• Very high doses of vitamin C may increase oxalate levels in urine

Special Precautions

• Monitor renal function in patients with a history of kidney stones
• Inform laboratory staff of glutathione or high-dose vitamin C use, as it may affect certain biochemical assays
• Consult a healthcare provider before use in pregnancy, lactation, or chronic medical conditions

Drug Interactions

• May reduce the efficacy of certain chemotherapeutic agents by acting as an antioxidant
• May enhance iron absorption (via vitamin C), caution in hemochromatosis
• Glutathione may interact with nitroglycerin, leading to potential hypotension

Storage

• Store below 25°C in a dry place
• Keep sachets in original packaging until use
• Protect from direct sunlight and moisture
• Keep out of reach of children

Scientific Support

• Matsuyama et al. 2014 – Glutathione skin-lightening and antioxidant action
• Rizwan et al. 2018 – Synergistic antioxidant role of glutathione and vitamin C

Summary

NeoTad sachets provide an effective antioxidant combination of glutathione and vitamin C. Their synergistic action supports immune function, combats oxidative stress, and contributes to improved skin tone and tissue repair. Safe for daily use, NeoTad is a valuable addition to wellness routines, provided precautions are followed and medical guidance is obtained in special populations.