Samyr 400 mg. 20 capsules

Description

Samyr 400 mg. 20 capsules

Composition

Each capsule of Samyr 400mg contains the active substance Ademetionine 1,4-butanedisulfonate equivalent to 400mg of S-Adenosyl-L-methionine. The other ingredients include microcrystalline cellulose, magnesium stearate, and colloidal anhydrous silica.

Description

Samyr 400mg is a medication that comes in the form of hard gelatin capsules. The capsules are filled with a white to off-white powder and are packaged in blister packs. Each pack contains 20 capsules.

Indications

Samyr 400mg is indicated for use in the treatment of depression, liver diseases, and osteoarthritis. It is also used as a supplement in conditions where there is a deficiency of S-Adenosyl-L-methionine in the body.

Mechanism of action

S-Adenosyl-L-methionine, the active ingredient in Samyr 400mg, is a naturally occurring substance in the body. It is involved in several biochemical reactions, including the synthesis of neurotransmitters, proteins, and phospholipids. It also has an anti-inflammatory and analgesic effect which helps in the management of osteoarthritis.

Dosage and Administration

The recommended dosage of Samyr 400mg is one capsule taken orally twice a day, preferably on an empty stomach. The dosage may be increased to two capsules twice a day in cases of severe depression or liver diseases. The capsules should be swallowed whole with a glass of water and should not be chewed or crushed.

Contraindications

Samyr 400mg is contraindicated in patients with known hypersensitivity to Ademetionine or any of the other ingredients of the medication. It is also contraindicated in patients with bipolar disorder as it may induce a manic episode. Furthermore, it should not be used in children and adolescents under the age of 18 years due to the lack of data on safety and efficacy.

Precautions

Before starting treatment with Samyr 400mg, patients should inform their doctor if they have a history of gastrointestinal disorders, kidney diseases, or if they are taking any other medications. It should be used with caution in elderly patients and those with a history of psychiatric disorders. Regular monitoring of liver function is recommended during treatment.

Side effects

The most common side effects of Samyr 400mg include nausea, diarrhea, and abdominal discomfort. Other less common side effects include dizziness, dry mouth, and insomnia. In rare cases, it may cause skin reactions such as rash and pruritus. If any of these side effects persist or worsen, patients should contact their doctor immediately.

Overdose

In case of overdose, symptoms may include nausea, vomiting, and abdominal pain. Patients should seek immediate medical attention. Treatment of overdose is symptomatic and supportive.

Storage

Samyr 400mg should be stored at room temperature, away from heat and moisture. It should be kept out of reach of children and pets.