Description
Tamoxifen tablets 20 mg #30
Pharmaceutical Dosage Form
Medication Description
This medicine is an anti-estrogenic medication widely used for medical purposes. It acts as a regulator of estrogen receptor activity, displaying both agonistic and antagonistic effects.
Pharmacologic Effect
Tamoxifen blocks estrogen receptors, competing with estradiol for binding sites on cytoplasmic estrogen receptors in various tissues including the breast, uterus, vagina, anterior pituitary gland, and estrogen receptor-rich tumors. The tamoxifen-receptor complex inhibits DNA synthesis, suppressing cell division and leading to tumor cell destruction.
Tamoxifen Properties
Sportsmen use this medicine to counteract the side effects of steroid aromatization. Tamoxifen regulates the hypothalamus-pituitary-testes axis, similar to Clomid and Cyclophenyl. It can also help maintain cholesterol balance and reduce gynecomastia risk.
Dosage
- Light course of 30 days: Take 20 mg for 15 days, then 10 mg for another 15 days.
- Moderate course of 45 days: Take 20 mg for 30 days, then 10 mg for another 15 days.
- Heavy course of 45 days: Take 40 mg for 15 days, then 20 mg for 15 days, then 10 mg for another 15 days.
- Very heavy course of 45 days: Take 80 mg for 3 days, then 40 mg for 12 days, then 20 mg for 15 days, then 10 mg for 15 days.
For men: Dosage ranges from 10 to 30 mg daily to counteract estrogenic side effects. For gynecomastia, 40 mg daily in two doses may be used. During PCT, up to 40 mg daily in two doses is sufficient.
For women: Tamoxifen is used for breast cancer treatment.
Side Effects
Possible manifestations include nausea, vomiting, cholestatic syndrome, hepatitis, depression, dizziness, headaches, and more. Long-term high-dosage use may lead to these side effects.
Contraindications and Use for Medical Purposes
Prescribed for breast cancer in women and males after castration, kidney cancer, melanoma, ovarian cancer, and prostate cancer in opposition to other medications. Not suitable for thrombosis, pregnant women, and those hypersensitive to tamoxifen.
Storage Terms and Conditions
Store in original packaging at temperatures not exceeding +25°C, out of reach of children. Shelf life is 36 months.
Enhancing the Therapeutic Efficacy of Tamoxifen Citrate Loaded Span-Based Nano-Vesicles on Human Breast Adenocarcinoma Cells
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