Magnesium sulfate 250 mg/ml 10 amp 5 ml.

Description

Magnesium Sulfate 250 mg/ml, 10 amp 5ml Solution

Composition

Each ampoule of Magnesium Sulfate 250 mg/ml, 10 amp 5 ml solution contains 250 mg of magnesium sulfate per ml. The solution is available in packs of 10 ampoules, each ampoule containing 5ml of the solution. Other ingredients include water for injections. The medicinal product is a clear and colorless solution free from visible particles.

Therapeutic Indications

Magnesium Sulfate 250 mg/ml, 10 amp 5 ml solution is indicated for the prevention and control of seizures (fits) in pre-eclampsia or eclampsia, conditions that can occur during pregnancy. The solution is also used to treat severe acute magnesium deficiency and as an anticonvulsant for pediatric acute nephritis.

Contraindications

This medication is contraindicated in patients with hypersensitivity to the active substance or to any of the excipients. It is also contraindicated in patients with severe renal impairment, heart block or myocardial damage, and in patients with hypermagnesemia. Additionally, it should not be administered during the two hours preceding delivery in pregnant women with pre-eclampsia or eclampsia.

Precautions

Magnesium sulfate should be used with caution in patients with renal impairment and those with a history of heart disease. Patients receiving this medication should be monitored for signs of magnesium toxicity, which can include flushing, sweating, hypotension, depressed reflexes, flaccid paralysis, hypothermia, circulatory collapse, cardiac and central nervous system depression, and respiratory paralysis. To prevent hypermagnesemia, blood concentrations should be monitored. Use of magnesium sulfate in pregnant women should be considered only if the potential benefits outweigh the potential risks to the fetus.

Interactions

Magnesium sulfate can interact with several other medications. It can enhance the neuromuscular blocking effect of drugs such as tubocurarine and succinylcholine. Concurrent use with nifedipine can lead to severe hypotension. Use of magnesium sulfate with digitalis glycosides can increase their toxicity. Therefore, caution should be exercised in patients taking these medications concurrently with magnesium sulfate.

Adverse Reactions

Common adverse reactions to Magnesium Sulfate 250 mg/ml, 10 amp 5 ml solution include flushing, sweating, hypotension, depressed reflexes, flaccid paralysis, and hypothermia. In rare cases, patients may experience circulatory collapse, cardiac and central nervous system depression, and respiratory paralysis. If you experience any of these reactions, seek immediate medical attention.

Dosage and Administration

The dosage and mode of administration of Magnesium Sulfate 250 mg/ml, 10 amp 5 ml solution will vary depending on the patient’s condition and response to treatment. For the treatment of pre-eclampsia or eclampsia, the usual initial dose is 4-6 grams administered intravenously over 15-20 minutes, followed by an intravenous infusion of 1-2 grams per hour. For the treatment of magnesium deficiency, the dose will be adjusted based on the patient’s magnesium levels. Always follow your doctor’s instructions regarding dosage and administration of this medication.

Overdose

In case of overdose, the patient may experience symptoms such as flushing, sweating, low blood pressure, slow reflexes, flaccid paralysis, low body temperature, circulatory collapse, cardiac and central nervous system depression, and respiratory paralysis. Immediate medical attention is necessary in case of overdose.

Storage

Store Magnesium Sulfate 250 mg/ml, 10 amp 5 ml solution in a cool, dry place away from light and out of the reach of children. Do not freeze. Do not use if the solution is discolored or contains particles.