Description

Novirin tablets 500 mg, #40

The active ingredient of Novirin is inosine pranobex. Additionally, the medication contains inactive ingredients: magnesium stearate, povidone, and solani amylum. Novirin is available in the form of tablets (500 mg).

Use in Sports

• Immune system disorders are associated with the occurrence of chronic septic conditions and inflammatory-infectious diseases, leading to various declines in sports performance.
• In the practice of sports training, immunomodulators are prescribed for the treatment and prevention of secondary immunodeficiencies, overwork, correction of desynchronosis, and rehabilitation after injuries and surgical interventions.
• Using specific immunomodulators (such as thymus medications, interleukins, interferons, immunoglobulins) requires mandatory immunological analysis and medical supervision.
• Mild immunomodulators based on plant medications do not require a prior assessment of immune status; they are intended for preventing viral diseases during epidemically dangerous periods and immune disorders during training in mid-altitude conditions.
• Research and testing of new immunocorrecting medications are necessary to expand the possibilities of immunotropic correction for athletes.

Novirin Description

Novirin is an antiviral medication with an active ingredient that provides direct antiviral and immunity-modulating effects. It binds to the ribosomes of virus-affected cells, slowing down viral i-RNA production and inhibiting replication of DNA and RNA viruses. It also inhibits interferon formation.

The immunomodulatory effect results from its impact on T-lymphocytes, increased phagocytic activity of macrophages, and normalization of T-helper and suppressor cell populations. Novirin reduces viral load, normalizes immune cell production, activates interferon production, enhances resistance to infections, and limits infection spread.

Indications and Benefits

• Novirin is prescribed to individuals with low or normal immune status during viral infections:
• Adenoviral infections, parainfluenza, influenza, and other acute respiratory viral infections.
• Bronchitis of viral origin, mumps, measles, herpes simplex, subacute sclerosing panencephalitis, genital herpes, and more.
• The benefits include immunity enhancement, interferon production, antiviral action, and increased activity.

Novirin Contraindications

Novirin should not be taken by individuals intolerant to pranobex or other components of the medication. It’s contraindicated for patients with kidney/liver disorders, urolithiasis, gout, hyperuricemia, and children under one year old. Caution is advised for elderly patients due to potential hyperuricemia.

Method of Use and Dosage

Novirin is taken orally at regular intervals, preferably after meals. Tablets can be crushed, chewed, or dissolved in a small amount of water before taking.

The treatment duration depends on disease severity and relapse frequency. The average treatment duration is 5-14 days. The course can be repeated if necessary after a 7-10 day break. Novirin intake can last 1-6 months intermittently. The maximum adult dose is 4 g (8 tablets) per day.

Recommended dosages for various conditions:

• • Influenza, parainfluenza, and other acute respiratory viral infections: Adult patients – 2 tablets x 3-4 times a day, children – 50 mg/kg/day in 3-4 doses (course of 5-7 days).
  • Epidparotitis: 70 mg/kg/day in 3-4 doses (7-10 days).

Novirin Overdosage

Overdosage cases with Novirin have not been registered. Overdosage of Novirin may result in increased uric acid levels in the blood/urine. If overdosed, seek medical assistance and consider gastric lavage and symptomatic treatment.

Side Effects

Possible side effects include:

• Nervous system disorders: fatigue, headache, dizziness, insomnia, or drowsiness.
• Digestive tract disorders: abdominal pain, nausea, diarrhea, constipation.
• Skin changes: itching, redness, skin rashes, hives.
• Immune system disorders: allergies, angioneurotic edema.
• Liver and biliary tract disorders: elevated enzyme levels in blood.
• Musculoskeletal system disorders: joint pain.
• Urinary tract disorders: increased urine volume (polyuria).

Storage Terms and Conditions

Store Novirin in its original packaging at temperatures of 15–25°C. Shelf life is 2 years.

Clinical study of Gene-Eden-VIR/Novirin in genital herpes: suppressive treatment safely decreases the duration of outbreaks in both severe and mild cases