Description
Prefolic ampoules 50mg, 3ml, #6
Prefolic is a lyophilized liquid in 50 mg vials: folic acid, citric acid, glutathione, mannitol, methyl p-hydroxybenzoate, sodium hydroxide.
Solution water bottle: water for preparation of injection solutions.
Pharmacological Properties
Prefolic is a complex of folic and citric acids, glutathione, mannitol, methyl p-hydroxybenzoate, and sodium hydroxide. It supplies the body with folic acid and serves as a catalyst for its recovery processes. The drug increases the energy and efficiency of sports activities.
It participates as a coenzyme in various enzymatic reactions, plays an important role in the exchange of amino acids, the biosynthesis of purine and pyrimidine bases – a component of nucleic acids. This determines the importance of vitamin B9 for the normal functioning of tissue growth and development. Vitamin B9 is also important for the processes of hematopoiesis and embryogenesis. It has a positive effect on the work of the digestive tract.
Lack of vitamin B9 inhibits the process of hematopoiesis. Its absence causes a special type of anemia, affecting the digestive system.
Vitamin B9 is involved in the synthesis of muscle proteins. In bodybuilding, the requirement for folic acid is higher than in a normal lifestyle.
Prefolic is prescribed for macrocytic hyperchromic anemia, which occurs due to a lack of folic acid. It is also taken as part of a complex against anemia that arises from prolonged use of medications.
Indications for Use
Prefolic is used as a supplier of folic acid, a catalyst for chemical processes, and a stabilizer of metabolic processes during folate deficiency anemia.
It is the main blocker of side effects of methotrexate and aminopterin in cases of antidote therapy.
Prefolic is part of the Milan cocktail, which includes Epargresiovit, Inotin, Ezafosfina, and TAD 600. This cocktail is aimed at enzyme growth.
It is used as part of combination therapy for anemia, leukopenia, sprue, chronic gastroenteritis, and intestinal tuberculosis.
Mode of Application
Slow administration is recommended for intravenous use of Prefolic. The dosage for any administration type is 15 mg per day with an interval of every two days.
Exceptional dosages are used in antidote therapy. The dosage may be increased based on specific situations.
Gastro-resistant coated tablets are recommended for oral intake. The dosage scheme and duration are determined by a doctor.
Contraindications
Prefolic consists of several components and may cause individual intolerance in some patients.
Side Effects
Possible side effects include allergic symptoms, fever, tachycardia, lowered blood pressure, and anaphylactic shock.
Interaction with Other Medications
Prefolic is used in conjunction with cyanocobalamin for pernicious anemia to stimulate hematopoiesis.
Storage Conditions
Store at a temperature not exceeding 25°C, out of reach of children.
Additional Information
In cases of Addison-Birner’s disease, it’s recommended to use vitamin B12 alongside Prefolic.
Take necessary measures to avoid prolonged exposure to oxygen and bicarbonate discharge drugs when using a dropper.
In patients with epilepsy, anticonvulsant drugs can affect synthesis of megablasts and increase seizure risk.
Avoid driving or operating equipment that requires concentration while using Prefolic.
Consult a doctor before using Prefolic, as it may be harmful to health.
Folic Acid Supplementation and Pregnancy: More Than Just Neural Tube Defect Prevention
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