Description

Pyridoxine (vitamin B6) vials 50 mg / ml, 1 ml, #10

Pyridoxine Composition

• Active ingredient: Pyridoxine hydrochloride
• 1 ml of solution contains: 50 mg of pyridoxine hydrochloride
• Inactive ingredient: Disodium edetate, water for injections

Pharmaceutical Dosage Form: Injection

Basic Physical and Chemical Properties: Transparent colorless or slightly colored liquid

Biological Effects:

• Relieves abstinence symptoms after withdrawal of stimulants
• Participates in the formation of blood elements (erythrocytes)
• Facilitates glucose uptake by nerve cells, improves brain function, and stabilizes blood sugar levels
• Increases efficiency
• Necessary for protein metabolism and amino acid transamination
• Participates in the metabolism of fats
• Lowers cholesterol levels
• Provides a lipotropic effect; sufficient amount of pyridoxine is necessary for normal liver functioning

Pyridoxine in Sports

Protein synthesis, muscle growth, and carbohydrate utilization are dependent on the participation of pyridoxine. Research suggests that bodybuilders and weightlifters may require higher doses of pyridoxine to enhance performance and endurance.

Recommended Dosage

• Daily requirement for pyridoxine for adults: 2.0 mg
• Dosage for bodybuilders: Up to 10 mg per day
• Maximum allowable dosage: 100 mg per day (Dosages above 100 mg may lead to hypervitaminosis)

Properties

• Pyridoxine has a phosphorylated form and affects decarboxylation procedures, transamination, and deamination of amino acids.
• Plays a significant role in the synthesis of proteins, enzymes, hemoglobin, prostaglandins, serotonin, catecholamine, glutamic acid, GABA, histamine.
• Helps improve consumption of unsaturated fatty acids, lower cholesterol and lipids in the blood, and convert folic acid into its active form.

When We Require Vitamin B6

Vitamin B6 is required in the following cases:

• Taking antidepressants and oral contraceptives
• During periods of stress and increased physical activity
• Individuals who consume large amounts of alcohol or smoke heavily
• People suffering from AIDS, hepatitis, and radiation diseases

Manifestations of Vitamin B6 Deficiency

Symptoms of vitamin B6 deficiency include:

• Depression and abnormal irritability
• Seizures
• Slowdown and constant anxiety
• Poor sleep
• Dermatitis on the face, eyebrows, around the eyes, neck, and scalp
• Dry dermatitis around or on the nasolabial fold
• Seborrhea
• Glossitis and cheilosis with vertical lip cracks
• Stomatitis
• Poor appetite, nausea, and vomiting
• Conjunctivitis
• Polyneuritis of the upper and lower extremities

Medical Use

Pyridoxine is used for the following conditions:

• B6 hypovitaminosis
• Toxicosis during pregnancy
• Anemia and leukopenia of various etiologies
• Diseases of the nervous system
• Meniere’s disease, sea and air diseases
• Acute and chronic hepatitis
• Dermatological conditions: seborrhea-like and non-seborrheic dermatitis, lichen, neurodermatitis, and psoriasis
• Large doses prescribed for the treatment of autism and enuresis among children as part of combined antiepileptic medication therapy
• Taken against alcohol intoxication, as it contains pyridoxine

Symptoms of High Vitamin B6 Levels:

Excessive intake of vitamin B6 may result in the following symptoms:

• Allergic reactions, such as rash
• Increased gastric juice content at levels of 200-5000 mg or more, leading to numbness and tingling in the extremities.

Interaction with Other Medications:

If you are taking medications containing estrogens, you may require vitamin B6. Intake of anticonvulsant and anti-tuberculosis medications can lead to a deficiency of vitamin B6.

Incompatibility:

Do not mix pyridoxine solution in the same syringe with thiamine solution (vitamin B1), cyanocobalamin solution (vitamin B12), alkaline solutions, iron salts, or oxidizing element solutions. It is advisable to administer pyridoxine injections at least 12 hours after a thiamine injection.

It is not recommended to mix pyridoxine in the same infusion system or syringe with the following medications: adrenomimetics, ampicillin sodium salt, amphotericin B, ascorbic acid, other B vitamins, phytomenadione, dipyridamole, sodium oxyfericorbonone, phenothiazine derivatives (chlorpromazine), ethacrynic acid, and furosemide.

Shelf Life:

3 years.

Storage Conditions:

Store in its original packaging at a temperature not exceeding 25°C. Do not freeze.

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The Effect of Pyridoxine Hydrochloride Supplementation on Leptin, Adiponectin, Glycemic Indices, and Anthropometric Indices in Obese and Overweight Women