ZincPower inj. 10 ml. (Zink ampoules)

Description

ZincPower Injection 10 ml (10 vials)

Manufacturer

• Produced by: Korea Korus Pharm Co., Ltd.
• Country of Origin: South Korea
• Official Website: www.koruspharm.com (if available)

Composition

• Each 10 ml vial contains:
  • Active ingredient: Zinc (specific compound and concentration, such as zinc sulfate or gluconate, should be confirmed from the official instructions).
  • Other ingredients: Water for injection, sodium chloride (as needed for isotonicity).

Indications

ZincPower Injection is used for the treatment and prevention of zinc deficiency and associated medical conditions. Indications include:

• Treatment of zinc deficiency caused by malnutrition, chronic illnesses, or increased physiological demands.
• Support for the immune system during infections, recovery from surgery, or chronic disease states.
• Promotion of wound healing, tissue repair, and recovery from burns or trauma.
• Supportive therapy in skin conditions, such as acne or dermatitis, when linked to zinc deficiency.
• Adjunct therapy for improving hair and nail health in patients with severe zinc deficiency.

Dosage and Administration

• Administration route: Intravenous (I.V.) only.
• Typical dosage: The dosage should be individualized based on the patient’s clinical condition and zinc levels. Common recommendations include:
  • Adults: 2.5-10 mg of elemental zinc per day, depending on the severity of the deficiency.
  • Severe deficiency or critical care: Higher doses may be administered under strict medical supervision.
• Preparation: ZincPower must be diluted with a compatible solution, such as 5% dextrose or 0.9% sodium chloride, prior to administration.
• Infusion rate: Administer as a slow intravenous infusion over 30-60 minutes to prevent irritation or rapid zinc load.

Contraindications

ZincPower Injection is contraindicated in the following conditions:

• Known hypersensitivity to zinc compounds or any other ingredients in the formulation.
• Severe renal dysfunction without proper monitoring, as excess zinc may accumulate.
• Patients with hemochromatosis or conditions leading to excessive mineral accumulation.

Precautions and Warnings

• Use with caution in patients with kidney or liver impairment, as improper excretion may lead to toxicity.
• Monitor serum zinc levels regularly during treatment to avoid hyperzincemia.
• Patients should be advised to report symptoms of zinc overdose, including nausea, vomiting, or metallic taste in the mouth.
• Avoid mixing ZincPower with other medications in the same syringe or IV line to prevent incompatibilities.
• Pregnant and breastfeeding women should only use this medication under medical supervision, as zinc requirements may vary.

Adverse Effects

ZincPower Injection is generally well-tolerated, but the following side effects may occur:

• Local reactions: Pain, redness, or swelling at the injection site.
• Systemic reactions: Nausea, vomiting, dizziness, or a metallic taste in the mouth (rare).
• Metabolic effects: Hyperzincemia, which may lead to gastrointestinal upset or reduced absorption of other minerals like copper.
• Allergic reactions: Skin rash, urticaria, or, rarely, anaphylaxis.

Drug Interactions

• Concomitant use of zinc with certain antibiotics (e.g., tetracyclines, quinolones) may reduce the absorption and efficacy of both drugs. Administer these medications at different times.
• High doses of zinc can interfere with the absorption of copper and other trace elements, leading to imbalances.
• Consult with your healthcare provider for a complete list of potential interactions.

Pregnancy and Lactation

ZincPower can be used during pregnancy and lactation when the potential benefits outweigh the risks. Zinc is crucial for fetal development, but excessive doses should be avoided.

Overdose

In case of overdose, the following symptoms may occur:

• Nausea, vomiting, and diarrhea.
• Metallic taste in the mouth.
• Electrolyte imbalances, leading to complications.

Immediate supportive care and symptomatic treatment should be provided. Monitor serum zinc and electrolyte levels closely.

Storage

• Store at a temperature of 15-25°C (59-77°F).
• Protect from direct sunlight and do not freeze.
• Keep out of reach of children.
• Once opened, use the vial immediately. Discard any unused portion.

Patient Information

Patients should be informed about the purpose of the treatment and the importance of adhering to prescribed doses. Any unusual symptoms or adverse reactions should be reported to a healthcare professional immediately.