Description
TAD-600 mg/4 ml (Glutathione) – 10 Vials Solution
Manufacturer
- Produced by: Industria Farmaceutica Galenica Senese (IFGS).
- Country of Origin: Italy
- Distributed by: Authorized distributors worldwide, depending on the region.
Composition
- Each 4 ml vial contains:
- Active ingredient: Glutathione (reduced form) – 600 mg
- Other ingredients: Sodium hydroxide (for pH adjustment) and water for injection
Indications
TAD-600 (Glutathione) is a powerful antioxidant used in various clinical applications to protect cells from oxidative stress and support detoxification processes. Indications include:
- Management of liver diseases, including alcoholic liver disease, fatty liver, and hepatitis
- Detoxification support for patients exposed to toxins, heavy metals, or chemotherapy
- Adjunct therapy in neurodegenerative diseases, such as Parkinson’s disease
- Skin brightening (off-label use in some regions)
- Supportive therapy in chronic fatigue syndrome and oxidative stress-related conditions
Dosage and Administration
- Administration route: Intravenous (IV) or intramuscular (IM)
- Dosage:
- For liver support: 600 mg IV/IM daily or as prescribed
- For detoxification: 600–1200 mg IV, 2–3 times per week
- For skin brightening (off-label): 600–1200 mg IV once or twice weekly, often combined with Vitamin C
- Preparation: Reconstitute the powder with 4 ml of sterile diluent. Use immediately after preparation
- Duration of therapy: Varies by condition (weeks to several months)
Contraindications
- Known hypersensitivity to glutathione or any formulation component
- Use in pregnancy or breastfeeding without medical supervision
- History of severe allergic reactions to similar substances
Precautions and Warnings
- Caution in renal impairment due to risk of accumulation
- Monitor liver function tests regularly
- Do not use as monotherapy in severe disease states
- Asthmatic patients may be at risk of bronchospasm
- Off-label use (e.g., skin whitening) requires medical oversight
Adverse Effects
- Local reactions: Pain, swelling, redness at injection site
- Allergic reactions: Rash, itching, rarely anaphylaxis
- Respiratory: Mild bronchospasm (rare)
- Neurological: Headache or dizziness (rare)
Drug Interactions
- May potentiate effects of certain chemotherapeutic agents – consult oncology specialist
- No significant interactions known, but always disclose all medications to the healthcare provider
Pregnancy and Lactation
Use only under medical advice if pregnant or breastfeeding. Safety profile not well-established in these populations.
Overdose
Symptoms such as nausea, vomiting, or dizziness may occur. Typically self-limiting. Provide supportive care if needed.
Storage
- Store at 15–25°C (59–77°F)
- Protect from moisture and light
- Do not freeze
- Use reconstituted solution immediately
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