TAD 600 mg/4ml (Glutathione) – 10 vials

Description

TAD 600 mg/4 ml (Glutathione) – 10 Vials Solution

Manufacturer

• Produced by: Industria Farmaceutica Galenica Senese (IFGS).
• Country of Origin: Italy
• Distributed by: Authorized distributors worldwide, depending on the region.

Composition

• Each 4 ml vial contains:
  • Active ingredient: Glutathione (reduced form) – 600 mg.
  • Other ingredients: Sodium hydroxide (for pH adjustment) and water for injection.

Indications

TAD (Glutathione) is a powerful antioxidant used in various clinical applications to protect cells from oxidative stress and support detoxification processes. Indications include:

• Management of liver diseases, including alcoholic liver disease, fatty liver, and hepatitis.
• Detoxification support for patients exposed to toxins, heavy metals, or chemotherapy.
• Adjunct therapy in neurodegenerative diseases, such as Parkinson’s disease.
• Skin brightening (off-label use in some regions).
• Supportive therapy in chronic fatigue syndrome and oxidative stress-related conditions.

Dosage and Administration

• Administration route: Intravenous (IV) or intramuscular (IM).
• Dosage:
  • For liver support: 600 mg IV/IM daily or as prescribed by the healthcare provider.
  • For detoxification: 600-1200 mg IV, 2-3 times per week, depending on the level of exposure to toxins.
  • For skin brightening (off-label): 600-1200 mg IV once or twice per week, typically combined with Vitamin C.
• Preparation: Reconstitute the powder in the vial with 4 ml of the provided diluent or a compatible sterile solution before administration. Ensure the solution is clear and free of particles.
• Duration of therapy: The treatment course varies depending on the condition being treated, ranging from a few weeks to several months.

Contraindications

TAD is contraindicated in the following conditions:

• Known hypersensitivity to glutathione or any components of the formulation.
• Pregnant or breastfeeding women without prior consultation with a healthcare provider.
• Patients with a history of severe allergic reactions to similar substances.

Precautions and Warnings

• Use with caution in patients with renal impairment, as improper excretion may lead to accumulation.
• Monitor liver function tests regularly during therapy to assess effectiveness and avoid toxicity.
• Avoid using glutathione as a sole therapy for severe conditions; it is intended as adjunct therapy.
• Patients with asthma should be monitored closely, as glutathione may trigger bronchospasm in rare cases.
• Off-label use, such as for skin brightening, should be approached cautiously and under medical supervision.

Adverse Effects

TAD is generally well-tolerated, but some patients may experience mild side effects, including:

• Local reactions: Pain, swelling, or redness at the injection site.
• Allergic reactions: Skin rash, itching, or, in rare cases, anaphylaxis.
• Respiratory effects: Mild bronchospasm or shortness of breath (rare).
• Neurological effects: Dizziness or headache (rare).

Drug Interactions

• Glutathione may enhance the effects of certain chemotherapeutic agents. Consult with an oncologist if used during cancer therapy.
• No significant interactions with other medications have been reported, but always inform your healthcare provider of all medications you are taking.

Pregnancy and Lactation

The safety of TAD during pregnancy and lactation has not been fully established. Use only if the potential benefits outweigh the risks, as determined by a healthcare provider.

Overdose

In case of overdose, symptoms such as nausea, vomiting, or dizziness may occur. These effects are usually self-limiting and do not require specific treatment. Monitor the patient closely and provide symptomatic care as needed.

Storage

• Store at a temperature of 15-25°C (59-77°F).
• Protect from direct sunlight and moisture.
• Do not freeze.
• Reconstituted solutions should be used immediately. Discard any unused portion.