Description

Biofosfina 20 sachets 5.6 g

Composition

Each sachet of Biofosfina contains 5.6 g of formulation with the active ingredient disodium phosphate. Inactive components include sweeteners, anti-caking agents, and flavoring substances to aid solubility and palatability. The powder is intended to be dissolved in water for oral administration.

Indications

Biofosfina is indicated for the treatment of hypophosphatemia, a medical condition characterized by low serum phosphate levels. It is also used in managing specific metabolic disorders, supporting nutritional supplementation when dietary phosphate is insufficient, and for patients with increased phosphate requirements under clinical supervision.

Contraindications

• Hyperphosphatemia (elevated serum phosphate levels)
• Severe renal impairment or chronic kidney disease
• Congestive heart failure or other significant cardiac conditions
• Hypersensitivity to disodium phosphate or any excipients

Warnings and Precautions

• Monitor serum phosphate, calcium, and renal function during prolonged use
• Caution in patients with hypertension or sodium-sensitive conditions, as phosphate salts may affect fluid and electrolyte balance
• Do not exceed recommended dosage
• Consult your healthcare provider before use during pregnancy or lactation

Dosage and Administration

• Typical adult dose: 1 sachet dissolved in a glass of water, once or twice daily, depending on clinical evaluation
• Use exactly as prescribed by your healthcare provider
• Administer with food to reduce gastrointestinal discomfort and improve absorption
• Consume the solution immediately after preparation

Instructions for Use

Empty the contents of one sachet into a glass of approximately 150–200 ml of water. Stir until fully dissolved. The solution should be taken immediately and not stored for later use.

Side Effects

Common side effects may include:

• Nausea
• Abdominal cramps
• Flatulence or diarrhea

Rare but serious side effects include:

• Muscle cramps or weakness
• Mood or mental changes
• Irregular heartbeat

If any of these occur, discontinue use and seek immediate medical advice.

Interactions

• May interact with diuretics, antacids containing aluminum, calcium or magnesium, and bisphosphonates
• May reduce the absorption of certain antibiotics (e.g., tetracyclines, fluoroquinolones)
• Always inform your healthcare provider about all medications and supplements being taken

Overdose

In case of overdose, symptoms may include:

• Severe abdominal pain
• Vomiting
• Blood in urine
• Neuromuscular symptoms (e.g., weakness, tetany)

Seek immediate medical attention or contact a poison control center.

Storage

• Store at controlled room temperature (15–25°C)
• Protect from moisture and heat
• Keep sachets in original packaging until use
• Keep out of reach of children

Scientific References

• Hypophosphatemia: Pathophysiology and Management – NCBI
• Phosphate supplementation in clinical nutrition – PubMed