Polyoxidonium powder for injections 6 mg, #5

Description

Polyoxidonium powder for injections 6 mg, #5 Solution

Composition

Each vial of Polyoxidonium powder for injections contains 6 mg of Azoximer bromide as an active substance. An auxiliary substance in the composition includes Mannitol.

Description

Polyoxidonium powder for injections is a lyophilisate for preparing a solution for intramuscular and intravenous injections. It appears as a white or nearly white powder or a porous mass. The powder is packaged in 6 mg vials, with five vials in a package (#5).

Pharmacological Group

Polyoxidonium belongs to the group of immunomodulating agents. Its active ingredient, Azoximer bromide, is known for its immunostimulating properties.

Pharmacological Properties

Polyoxidonium is designed to stimulate the immune system and enhance the body’s resistance to bacterial, viral, and fungal infections. It promotes the activation of natural killer cells, T- and B-lymphocytes, macrophages, and other elements of the immune system. The medication also has detoxifying properties, helping to remove harmful substances from the body.

Indications for Use

Polyoxidonium is indicated for use in the treatment and prevention of various infections, including acute and chronic inflammatory diseases of bacterial, viral, and fungal origin. It is also used in complex therapy of allergies, autoimmune diseases, and in the pre- and post-operative periods to prevent complications.

Contraindications

The medication is contraindicated for individuals with hypersensitivity to any component of the drug. It should not be used in patients with severe autoimmune diseases, during acute infectious diseases, and in pregnancy and lactation.

Dosage and Administration

The method of administration and dosage of Polyoxidonium powder for injections depend on the patient’s age, weight, and the nature of the disease. Generally, the medication is administered intramuscularly or intravenously, following the reconstitution of the powder with sterile water for injection or 0.9% sodium chloride solution. The usual dose for adults is 6-12 mg, while for children, the dose is calculated based on their body weight.

Side Effects

Although Polyoxidonium is generally well-tolerated, some patients may experience side effects, including fever, chills, and allergic reactions. Most of these side effects are mild and transient.

Overdose

No cases of overdose have been reported so far. However, in case of an overdose, symptomatic treatment is recommended.

Interaction with Other Drugs

Polyoxidonium can be used in combination with other medications, including antibiotics, antiviral, antifungal, antihistamine, and immunosuppressive drugs. However, the simultaneous use of Polyoxidonium and immunosuppressants should be under the close supervision of a doctor.

Special Instructions

Polyoxidonium does not affect the ability to drive vehicles and operate machinery. However, it should be used with caution in patients with severe hepatic and renal insufficiency.

Storage Conditions

Polyoxidonium powder for injections should be stored at a temperature not exceeding 25°C, in a dry, dark place, out of the reach of children.

Shelf Life

The shelf life of Polyoxidonium powder for injections is 3 years from the date of manufacture. After the expiration date, the medication should not be used.

Packaging

Polyoxidonium powder for injections is packaged in 5 glass vials, each containing 6 mg of the drug. The vials are placed in a carton box along with instructions for use.

Manufacturer

The medication is manufactured by Petrovax Pharm, a Russian pharmaceutical company specializing in the production of immunobiological drugs.

Prescription Status

Polyoxidonium powder for injections is a prescription-only medication.